Anyone know of a gel that helps with ED?
where it’s already easily available—please share your experience with me, particularly how effective it is, how long the effect lasts, and what your partner thinks, at michael@mcastleman.com. As more information becomes available, I will post more about Eroxon. “FDA Approves Gel to Treat Erectile Dysfunction,” New York Times, June 27, 2023.
| Crosslinker | Used For | Effect on Gel Structure | Toxicity Level | Food Grade |
|---|---|---|---|---|
| Glutaraldehyde | Laboratory, research | Strong, permanent crosslinking | High | No |
| Calcium Ions | Pectin, Carrageenan | Strengthens gel, influences firmness | Low | Yes |
| Magnesium Ions | Agar, Carrageenan | Increases gel elasticity | Low | Yes |
| Aluminum Sulfate | Some commercial gels | Gel stabilization | Medium | Varies |
“Efficacy and Safety of MED2005, a Topical Glyceryl Trinitrate Formulation, in the Treatment of Erectile Dysfunction: A Randomized Crossover Study,” Journal of Sexual Medicine (2018) 15:167. You may have heard of a new erectile dysfunction therapy known as Eroxon (MED 3000) that the FDA recently approved for over-the-counter use.
Understanding Topical ED Therapies: Why gels? The rationale behind topical delivery
The result of using Viagra can be a stronger erection. Topical nitroglycerin can work anywhere that you apply it. That’s why you should wear gloves or another protective covering (like a finger covered in plastic wrap) before putting it on your penis. Squeeze a pea-sized dot on your finger and apply to the head of your penis. Typically, your body will rapidly absorb the nitroglycerin.
Is there a side effect to an erection gel?
If enough time passes after application, the gel shouldn’t affect your partner. One of the benefits to nitroglycerin gel is that it works faster than ED treatments such as Viagra. However, it also doesn’t last very long in the body — usually only a few minutes. If you keep applying it, it’s possible you could use excessive amounts. The problem is: Since there isn’t much research on how you can safely use it, it’s difficult to say how much is too much and what the side effects are from overuse.
High expectations, low results
That’s why it’s important to talk with your doctor before applying topical nitroglycerin. Although some research points to the effectiveness of nitroglycerin gel or cream for improving the symptoms of ED, it’s currently not approved by the FDA as a treatment for ED. If you have ED or think you may have ED, it’s important to talk with a doctor about any treatment options. They can talk with you about the range of options, including lifestyle modifications, counseling, oral agents, penis pumps, surgery, and implants. Posted July 2, 2023 Reviewed by Tyler Woods Topical, over-the-counter Eroxon gel may help some men with erection problems. It is a topical gel marketed in Europe and the UK as a faster way to gain an erection versus Viagra or Cialis, and their generic forms sildenafil and tadalafil, respectively.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Gold | 50 mg | 60 + 4 Pills | 171.14€ 162.99€ | |
| Levitra Generic | 60mg | 30 + 2 Pills | 109.43€ 104.22€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Cialis Generic | 20mg | 60 + 6 Pills | 117.76€ 112.15€ | |
| Cialis Generic | 60mg | 20 Pills | 65.61€ 62.49€ | |
| Levitra Generic | 20mg | 360 + 10 Pills | 458.44€ 436.61€ | |
| Levitra Soft Tabs | 20mg | 120 + 8 Pills | 288.52€ 274.78€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Cialis Black | 80mg | 10 Pills | 43.27€ 41.21€ | |
| Cialis Generic | 5mg | 10 Pills | 29.39€ 27.99€ | |
| Cialis Generic | 40mg | 120 + 8 Pills | 206.98€ 197.12€ | |
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Levitra Generic | 60mg | 270 + 10 Pills | 714.53€ 680.50€ | |
| Cialis Generic | 60mg | 60 + 4 Pills | 145.06€ 138.15€ | |
| Cialis Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Viagra Professional | 100mg | 60 + 2 Pills | 146.74€ 139.75€ |
However, while this sounds like a fantastic erectile dysfunction therapy, does it work?
Final Thoughts
But it’s far from God’s gift to ED sufferers. It helped only one man in four, and worked only for mild ED. If those who responded started with an IIEF score of 17 and gained four points because of treatment, their post-treatment IIEF score was 21, heartening but still categorized as mild-to-moderate ED. Some men gained more than four points. Eroxon costs $20 per dose, which raises cost-benefit issues.
Penis sleeve
Unlike the Viagra family of ED medications, Eroxon is available over the counter. It takes 30 to 60 minutes for the Viagra family of drugs to take effect. With Eroxon, it’s five to 10 minutes. The most common side effects included: headache (8 percent of users), and nasal congestion (6 percent). So far, there is no information on how long Eroxon’s effect lasts.
Did you know about erection gel?
The manufacturer, Futura Medical of the U.K., says the gel “lasts long enough for successful intercourse in 65 percent of users.” That means it doesn’t allow intercourse in one-third of users. And among the 65 percent who can accomplish intercourse, some like it to last longer than others, but so far Eroxon’s duration of action remains unclear. Though FDA-approved, Eroxon is not yet available in the U.S. However, Amazon U.K. sells it (50 pounds, $62.50, plus international shipping). Before determining whether this particular gel works, we should discuss the history of topical erectile dysfunction gels and formulations. This very short discussion centers around the fact that we have tried to create topical versions of several medical therapies, including, for example, trimix, which is otherwise used as an injection into the penis, without any success – the simple fact is that, to date, we do not have a reliable therapy that functions topically.
- Innovations in ed gels include natural and herbal formulations.
- New delivery systems aim for enhanced penetration and reduced application time.
- They are continuously evolving to improve efficacy and patient experience.
- Research focuses on reducing side effects while maintaining effectiveness.
There have not been many studies performed in the United States that can show definitively that this gel will work; however, being that it has been used in Europe and the UK for some time now, we can expect that it may be effective for some patients. According to the manufacturer, the topical gel creates a warming sensation that stimulates penile tissue, allowing it to better engorge with blood. However, this is not typically the primary cause of erectile dysfunction.
Have questions?
That’s for four doses of the drug. On the Amazon U.K. site, the 77 ratings average 2.1 out of 5, not exactly a ringing endorsement. Still, Eroxon represents a new treatment possibility for men who would like to throw the dice on firmer erections. If you try it—especially 20 mg vardenafil readers in the U.K. Instead, most patients suffer from a lack of blood volume entering the penis in the first place (often caused by atherosclerosis).
| Gel Type | Gelation Temperature | Melting Temperature | Storage Stability |
|---|---|---|---|
| Gelatin | 10°C - 15°C | 20°C - 25°C | Moderate |
| Agar-Agar | 32°C - 40°C | >85°C | High |
| Carrageenan | 35°C - 40°C | >70°C | Moderate |
| Pectin | 4°C - 10°C | ~20°C | Good when stored cold |
Therefore, even if the tissues were more receptive to blood, there’s likely not enough supply to create and maintain an erection. As with many other therapies, including supplements, it’s most likely that this gel is working on men with either very mild or early-stage ED, or those who have ED with psychological roots.
- Ed gels are part of routine pre-procedural preparations in dentistry.
- They help reduce the need for more invasive anesthesia methods.
- Side effects are usually mild but may include allergic reactions.
- Patient education on proper use improves safety and effectiveness.
In other words, it’s doubtful that this would work for anyone who would otherwise have to take a significant dose of Viagra, Cialis, or their respective generic version. Of course, whether this gel can do something other products have failed to do over the years remains to be seen. That said, being it is FDA-approved for over-the-counter sale, it likely has a track record of some degree of safety. As with most relatively safe alternative therapies, we do not necessarily discourage their use if the patient understands that they may not work and, therefore, be a waste of money…and that they visit a reputable urologist or knowledgeable medical provider to discuss possible risks before starting any new therapy. If you are experiencing mild to moderate erectile dysfunction and these therapies have not succeeded, we encourage you to speak to Dr.
- The development of ed gels focuses on maximizing bioavailability.
- They often contain flavoring agents to mask medicine taste.
- Some gels are formulated with rapid onset in mind, within 30 seconds.
- They play a critical role in minimally invasive dental treatments.
Kapadia about starting comprehensive erectile dysfunction care, beginning with proper medications and moving on from there, based on results and needs. Eroxon® is a fast-acting treatment gel for erectile dysfunction (ED) that can be applied immediately before sexual activity and is clinically proven to help you get an erection within 10 minutes.
| Gel Type | Biodegradability | Environmental Concerns | Recycling Options |
|---|---|---|---|
| Gelatin | Biodegradable | Animal-derived waste | Composting |
| Agar-Agar | Biodegradable | None significant | Composting |
| Carrageenan | Biodegradable | Seaweed resource impact | Composting |
| Pectin | Biodegradable | Fruit waste | Composting |
As the first-and-only ED gel, Eroxon® offers men and their partners results without the side effects of oral medicines or the inconvenience of getting a prescription. Clinically proven to work within 10 minutes† No one should be forced to plan ahead to enjoy intimate moments, and today’s treatments make it difficult to connect spontaneously.
Use caution with unproven ED treatments
The treatment works only for those with mild ED, and for them, not very well. It's been available in England for some time. Its rating on Amazon UK is just 2.1 out of 5—not very good. On June 13, 2023, the Food and Drug Administration approved a topical gel, Eroxon, for fast-acting treatment of erectile dysfunction (ED). That’s good news for men who want erections and don’t respond to other medications.
1. Clinical validation
In addition, Eroxon is available over the counter, so no doctor visits. The main study that led to the FDA approval showed pills to increase sex drive male that it helps only about one-quarter of men with mild ED, and among them, not all that much. English researchers recruited 232 men who suffered ED of various severities. They randomly received one of two treatments: Eroxon gel for four weeks, then following a one-week washout period, a placebo gel, or the placebo for a month, then a week later, Eroxon for a month (a double-blind crossover trial). Response was evaluated using the International Index of Erectile Function (IIEF), a 30-point standard measure of erection firmness, with 26-30 meaning no ED, and 10 or less severe ED.
What is Viagra gel and how does it work for erectile dysfunction?
At baseline, participants’ average IIEF score was 17, mild-to-moderate ED. By the end of the trial, 23 percent of the men showed at least a four-point increase in IIEF score. Those who responded noticed an effect within five to ten minutes after applying the gel. The researchers concluded that Eroxon “could be a useful treatment option in ED.” Yes, possibly, but…. If you have ED, Eroxon might be worth a try. Now, men and their partners have a fast-acting treatment option for ED: Eroxon® gel. Learn how Eroxon®’s easy-to-apply gel helps men and their partners move seamlessly from date night to pillow talk. ...leading to increased blood flow in the penis to help achieve and maintain an erection.
Practical Application and Experience
If you have ED and would like to try nitroglycerin gel, talk with your doctor first. There are many medications that cause negative side effects if you use them with nitroglycerin gel too. While there are quite a few, some of the main ones are sildenafil (Viagra), aspirin, or ergotamine, which treats migraine. Avoid using nitroglycerin gel if you have health conditions like anemia or hypotension. Using nitroglycerin can make these conditions worse.
Monitor for priapism
Nitroglycerin gel can cause unwanted side effects. You could also experience an allergic reaction where you apply the nitroglycerin. An allergic reaction could include redness, swelling, or itching. If you experience these symptoms, stop using nitroglycerin gel immediately. Remove any excess and avoid touching the nitroglycerin with your hands to ensure your symptoms don’t get worse.
Clinical trial outcomes
Seek immediate medical attention if your symptoms don’t improve after a few minutes or you’re having trouble breathing. No, nitroglycerin doesn’t work the same as Viagra. Your body breaks nitroglycerin down into nitric oxide. This compound expands the blood vessels to promote more blood flow. Viagra is a phosphodiesterase inhibitor that works to prevent PDE5, which limits blood flow to the penis.
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