I took 2 tablets of 20mg each sildenafil citrate andbarely had an effect. 3 hrs ago. Few years ago i took viagra 100 and
Use in children warning: Children generally should not take sildenafil; however, there are instances where the drug is considered the best treatment option.
- Sildenafil was originally developed for hypertension and angina.
- It was repurposed for erectile dysfunction after unintended effects were observed.
- The medication is marketed under various brand names like Viagra.
- Generic sildenafil citrate became available after patent expiration.
Talk with your child’s doctor to better understand the benefits and risks associated with this treatment option. Sildenafil oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.
| Parameter | Value | Unit | Description |
|---|---|---|---|
| Tmax | 30-120 | minutes | Time to peak plasma concentration |
| Half-life | 3-5 | hours | Time for plasma concentration to halve |
| Bioavailability | ~40 | % | Amount absorbed unchanged |
| Protein Binding | 96 | % | Extent bound to plasma proteins |
Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.
- Common side effects include headaches, flushing, and nasal congestion.
- Serious side effects are rare but may involve vision changes or priapism.
- Alcohol can reduce the effectiveness of sildenafil and increase side effects.
- Keep the medication out of reach of children and store in a cool, dry place.
To find out how this drug might interact with something else you’re taking, talk with your doctor or pharmacist.
Adverse effects
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine. Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Dose pédiatrique
Tell your care team right away if you have any change in your eyesight or hearing. This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
What does Viagra do for ED?
Contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage. If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medication, you should refrain from further activity and call your care team as soon as possible. Using this medication does not protect you or your partner against HIV or other sexually transmitted infections (STIs). Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects. Examples of drugs that can cause interactions with sildenafil are listed below.
- Sildenafil is sometimes used off-label for pulmonary arterial hypertension.
- Its use in this condition requires medical supervision.
- The medication may interact with certain antifungal or antibiotic drugs.
- Always inform your healthcare provider about all medications taken.
Do not take these drugs with sildenafil. Doing so can cause dangerous effects in the body.
- The active ingredient, sildenafil citrate, is a white to off-white powder.
- It has a molecular weight of approximately 473.6 g/mol.
- The medication is synthesized through complex chemical processes.
- Pharmaceutical quality control ensures batch consistency.
Nitrates, such as isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level.
| Condition | Requirement | Reason |
|---|---|---|
| Temperature | Store below 30°C (86°F) | Maintain tablet stability |
| Humidity | Keep in a dry place | Prevent tablet degradation |
| Light exposure | Store in original container | Protect from light |
| Shelf life | Typically 2-3 years | Ensure efficacy |
Guanylate cyclase stimulators, such as riociguat.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Viagra Generic | 50mg | 30 + 4 Pills | 54.26€ 51.68€ | |
| Viagra Generic | 25mg | 60 + 4 Pills | 71.99€ 68.56€ | |
| Viagra Generic | 150mg | 360 + 10 Pills | 423.48€ 403.31€ | |
| Kamagra Polo | 100mg | 20 Pills | 83.56€ 79.58€ | |
| Viagra Generic | 100mg | 120 + 6 Pills | 149.50€ 142.38€ | |
| Viagra Generic | 50mg | 120 + 6 Pills | 129.64€ 123.47€ | |
| Kamagra Polo | 100mg | 180 + 8 Pills | 446.52€ 425.26€ | |
| Kamagra Polo | 100mg | 272 + 12 Pills | 622.94€ 593.28€ | |
| Viagra Generic | 50mg | 360 + 10 Pills | 225.33€ 214.60€ | |
| Kamagra | 100mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ |
Side effects from sildenafil: Taking sildenafil with certain medications raises your risk for side effects from sildenafil.
Warnings & Precautions
Keep out of reach of children and pets. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Autres utilisations
Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more. Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals. Sildenafil oral tablet is available as a brand-name drug and as a generic drug. Sildenafil comes in three forms: an oral tablet, an oral suspension (liquid), and an injection that’s only given by a doctor. Sildenafil oral tablet is used to treat erectile dysfunction (ED).
Other Medical Problems
It’s also used to treat pulmonary arterial hypertension (PAH). It comes in the form of a tablet and suspension (liquid). It also comes in an intravenous (IV) form, which is only given by a doctor. Sildenafil oral tablet is available as the brand-name drugs Viagra and Revatio. It’s also available as a generic drug. This is because the amount of sildenafil in your body is increased.
8.6 Renal Impairment
If they’re more severe or don’t go away, talk with your doctor or pharmacist. Serious side effects and their symptoms can include the following: Symptoms can include:blurry visionconfusiondizzinessfaintinglightheadednessnausea or vomitingsleepinessweakness Increased shortness of breath or trouble breathing Priapism (an erection that lasts more than 4 hours) Symptoms can include:sudden vision loss in one or both eyes sudden vision loss in one or both eyes Symptoms can include:sudden hearing losstinnitus (ringing in your ears)dizziness Heart problems, such as heart attack, stroke, or irregular heart rate. Symptoms can include:chest painshortness of breathdizzinesstrouble speakingconfusionnausea or vomitingfeeling lightheaded Priapism warning: This drug can cause priapism, which is an erection that won’t go away. If you have an erection that lasts more than 4 hours, call 911 or go to the nearest emergency room. If it’s not treated right away, this condition can cause permanent damage to your penis. HIV drugs, such as ritonavir, indinavir, saquinavir, or atazanavir.Increased side effects can include low blood pressure, dizziness, or vision problems. They can also include erections that last longer than normal. Increased side effects can include low blood pressure, dizziness, or vision problems. Certain antibiotics, such as clarithromycin or erythromycin.Increased side effects can include low blood pressure, dizziness, or vision problems. Certain antifungals, such as ketoconazole or itraconazole.Increased side effects can include low blood pressure, dizziness, or vision problems. Side effects from other drugs: Taking sildenafil with certain medications raises your risk for side effects from these drugs.
| Brand Name | Manufacturer | Dosage Forms | Price Range (USD) | Available Regions |
|---|---|---|---|---|
| Viagra | Pfizer | 25, 50, 100 mg | 30-50 per tablet | Worldwide |
| Revatio | Pfizer | 20 mg tablets | 40+ per tablet | Mainly for pulmonary hypertension |
| Kamagra | Ajanta Pharma | 50, 100 mg | 0.5-2 per tablet | Asia, Middle East |
| Generic Sildenafil | Multiple manufacturers | 25, 50, 100 mg | 0.3-3 per tablet | Global |
Alpha-blockers, such as terazosin, tamsulosin, doxazosin, alfuzosin, or silodosin.Increased side effects can include a drop in blood pressure, or fainting.
What special precautions should I follow?
Sudden vision loss warning: This drug can cause sudden vision loss in one or both eyes. This can be a sign of a serious eye problem. If this occurs, stop taking sildenafil and call your doctor right away. Sudden hearing loss warning: This drug can cause hearing loss, tinnitus (ringing in your ears), or dizziness. If you have sudden hearing loss with or without tinnitus or dizziness, stop taking sildenafil and call your doctor right away. Increased side effects can include a drop in blood pressure, or fainting.
Route of administration
Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. Generic oral tablets are available for both conditions, but the brand-name drugs each treat only one of the conditions. Viagra: This drug is used to treat ED. With ED, you’re unable to get or maintain an erection.
Effectiveness and safety
Revatio: This drug is used to treat PAH. With PAH, the blood pressure in your lungs is too high. Your heart has to work very hard to pump blood into your lungs. Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. A class of drugs is a group of medications that work in a similar way.
Altitude sickness
These drugs are often used to treat similar conditions. Sildenafil works in different ways, depending on the condition it’s being used to treat. For ED: Sildenafil works by increasing blood flow to the penis. This helps you get or maintain an erection. Sildenafil only works for ED if you’re sexually aroused. Blood pressure drugs, such as amlodipine.Increased side effects can include blood pressure that’s too low. Increased side effects can include blood pressure that’s too low. Other drugs for erectile dysfunction, such as avanafil, tadalafil, or vardenafil.Increased side effects can include low blood pressure or erections that last longer than normal Increased side effects can include low blood pressure or erections that last longer than normal Disclaimer: Our goal is to provide you with the most relevant and current information.
12.3 Pharmacokinetics
For PAH: Sildenafil works by relaxing the muscles and opening up the blood vessels in your lungs. This sildenafil premature ejaculation decreases the blood pressure in your lungs. Sildenafil slows down the progression of your illness. It also makes you more able to exercise. Sildenafil can be used as early as 4 hours before sex and as late as 30 minutes before sex.
Pulmonary hypertension
However, it is recommended to use this drug within an hour before sex. Sildenafil should not be taken for ED more than once in a 24-hour period. But if you have certain medical conditions or are taking other drugs, your doctor may recommend that you take this drug less often than once a day. It is important to note that certain foods, particularly foods high in fat, can cause the drug to work more slowly than normal. Sildenafil oral tablet doesn’t cause drowsiness, but it can cause other side effects, including: flushing (reddening and warming of the face) an erection that lasts longer than normal If these effects are mild, they may go away within a few days or a couple of weeks. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions.
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